Congressional panels to hold hearings on meningitis outbreak

WASHINGTON (Reuters) – Two congressional oversight committees will hold hearings next week on the deadly U.S. meningitis outbreak linked to tainted steroid injections and one panel has invited an official from the compounding pharmacy involved, aides said on Monday.

The House of Representatives Energy and Commerce Committee expects to hear testimony from Food and Drug Administration commissioner Margaret Hamburg on November 14.

The Republican-led panel has also invited Barry Cadden, co-owner of the New England Compounding Center, and James Coffey of the Massachusetts Board of Registration in Pharmacy, to appear.

A spokeswoman for the Massachusetts Department of Health did not say immediately whether Coffey would testify. A lawyer for Cadden was not immediately available for comment.

On November 15, the Democratic-controlled Senate Health, Education, Labor and Pensions Committee will hold its own hearing. It has invited a half-dozen witnesses including Hamburg, Cadden and health officials from Massachusetts and the U.S. Centers for Disease Control and Prevention.

Both committees have been investigating the outbreak that has sickened 419 people, killing 30, in 19 states, according to the CDC.

Lawmakers are trying to determine why NECC was allowed to continue operating after federal and state officials had identified problems at its facility including potential health risks posed by its production of injectable drugs.

The committees are also considering possible legislative action to enhance the FDA’s oversight powers over compounding pharmacies, which are regulated mainly by state pharmacy boards.

(Reporting by David Morgan and Toni Clarke; Editing by Mohammad Zargham)

Medications/Drugs News Headlines – Yahoo! News

Read More..

Profits fall at Marks and Spencer

6 November 2012 Last updated at 03:30 ET

Marks and Spencer, the UK’s biggest clothing retailer, has posted pre-tax profits of £290m for the six months to the end of September, down 9.7% from the same period last year.

Group sales were up 0.9% to £4.7bn, with much of the growth coming from the food side of the business.

Food sales were up 3.4%, or 1.1% on a like-for-like basis, which strips out the effect of new stores.

Clothing and homeware like-for-like sales, were down 4.3%, M&S said.

Chief executive Marc Bolland said: “We are pleased to report a better performance across the business in the second quarter.

“We took steps to address the short term merchandising issues in General Merchandise [clothing and homeware] and as a result, we delivered an improved performance.

“Food outperformed the market on a like-for-like basis,” he said.

M&S said that the market had been challenging due to the bad weather, weak consumer confidence and pressure on customers’ disposable incomes.

And the summer’s major events had little or no effect on sales, M&S said.

“While the Jubilee and the Olympics improved the nation’s mood, they did not translate into higher sales.”

International sales were up 3.6% on a constant currency basis, with strong growth in China and India.

“The latest results from M&S are something of a mixed bag”, said Neil Saunders, managing director of retail consultancy, Conlumino.

“While the overall half year numbers look anaemic, there has been a material uplift in fortunes since the first quarter with even general merchandise moving into positive growth territory on a overall basis.”

While the group had benefited from improved High Street trading conditions and revamped stores, Mr Saunders warned that “it remains too early to call whether M&S is back on the path to sustainable growth.”

Continue reading the main story

It remains too early to call whether M&S is back on the path to sustainable growth”

End Quote Neil Saunders Retail analyst, Conlumino

M&S’s clothing performance contrasted sharply with that of discount fashion chain Primark, which saw like-for-like sales rise 3% and revenues rise 15% for the year to 15 September.

Management shake-up

On Monday, Mr Bolland announced further management changes, with Frances Russell, a former director of Philip Green’s Arcadia, moving up to director of womenswear, replacing Annette Browne, who has left the company.

Janie Schaffer, currently chief creative officer at Victoria’s Secret, will succeed Frances Russell as director of lingerie and beauty early next year.

The latest shake-up follows the appointment of John Dixon in October, who moved from food to become the head of general merchandise, replacing Kate Bostock.

In May, M&S reported its first fall in annual profits for three years, with pre-tax profits for the year to the end of March down 16% to £658m.

BBC News – Business

Read More..

Bomb shakes Damascus, opposition holds unity talks

AMMAN (Reuters) – A bomb exploded near army and security compounds in Damascus, Syrian television reported, and fractured opposition groups seeking to topple President Bashar al-Assad began unity talks abroad to win international respect and arms supplies.

The 50-kilogram (110-pound) bomb, near a large hotel in a heavily guarded district, was described by state media as an attack by “terrorists” – the government’s term for insurgents in the 19-month-old uprising against Assad.

Opposition activists said Sunday’s blast appeared to be the work of the Ahfad al-Rasoul (Grandsons of the Prophet) Brigade, an Islamist militant unit that attacked military and intelligence targets several times in the last two months.

The mainly Sunni rebels have carried out a series of bombings targeting government and military buildings in Damascus this year, extending the war into the seat of Assad’s power.

The Syrian conflict has aggravated divisions in the Islamic world, with Shi’ite Iran supporting Assad — whose Alawite faith derives from Shi’ite Islam — and U.S.-allied Sunni nations such as Saudi Arabia, Turkey and Qatar backing his foes.

The Syrian Network for Human Rights, an activist monitoring group, said government forces had killed 179 people on Sunday. It said most of the dead were civilians killed in shelling of Damascus suburbs and included 14 women and 20 children. The rest were rebels killed in battles in the capital and the northern provinces of Idlib and Aleppo.

Opposition campaigners said the Syrian army shelled rebel positions inside a Palestinian refugee camp on the edge of Damascus on Sunday, killing at least 20 people. They said the Yarmouk camp had become the latest battleground in the war.

In northern Idlib, opposition sources said rebels were forced to halt an offensive to take a big air base because of a shortage of ammunition, a problem that has dogged their campaign to cement a hold on the north by eliminating Assad’s devastating edge in firepower.

Islamist insurgents had launched the attack on the Taftanaz military airport at dawn on Saturday, using rocket launchers and at least three tanks captured from the military.

The Syrian government restricts journalists’ access in Syria, making it difficult to verify reports from the ground.

The Jaafar bin Tayyar Division, a rebel unit in Deir al-Zor, said its fighters had taken control of the al-Ward oilfield near the Iraqi border on Sunday, after overrunning a loyalist outpost that had 40 militiamen defending it.

Rebel commanders, former Syrian officials and the Syrian head of an oil services company familiar with oil production in the area said the fields, mostly not operational, had been under de facto rebel control for months.

FEARS OF WIDER CONFLAGRATION

The conflict began with peaceful protest rallies that morphed into armed revolt when Assad, whose family has ruled Syria since 1971, tried to stamp them out with military might. About 32,000 people have been killed, wide swathes of the major Arab state have been wrecked and the civil war threatens to widen into a regional sectarian conflagration.

The opposition talks that began in Qatar marked the first concerted attempt to meld feuding, disparate groups based abroad and coordinate strategy with rebels fighting in Syria.

Divisions between Islamists and secularists as well as between those inside Syria and opposition figures based abroad have foiled prior attempts to forge a united opposition and deterred Western powers from intervening militarily.

Analysts were skeptical the planned four days of opposition talks in the Qatari capital Doha would bring immediate results.

They aim to broaden the Syrian National Council (SNC), the largest of the overseas-based opposition groups, from some 300 members to 400, to pave the way for talks in Doha on Thursday including other anti-Assad factions to crystallise a coalition.

“The main aim is to expand the council to include more of the social and political components. There will be new forces in the SNC,” Abdulbaset Sieda, current leader of the Syrian National Council, told reporters in Doha ahead of the meeting.

The meetings would also elect a new executive committee and leader for the SNC, he said.

A Qatar-based security analyst, who asked not to be named, said the meetings would bring a small step forward, at most. “The Syrian National Council is just too divided,” he said.

In Cairo, the international mediator on Syria, Lakhdar Brahimi, called on Sunday for world powers to issue a U.N. Security Council resolution based on a deal they reached in June to set up a transitional Syrian government.

But Russian Foreign Minister Sergei Lavrov, speaking at the same news conference, dismissed the need for a resolution and said others were stoking violence by backing rebels. His comments highlighted the impasse over Syria’s civil war.

Russia and China, both permanent council members, have vetoed three Western-backed U.N. draft resolutions condemning Assad’s government for the violence. The other three permanent members are the United States, Britain and France.

(Additional reporting by Rania el Gamal and Regan Doherty in Qatar, Suleiman al-Khalidi in Amman; Editing by Philippa Fletcher and Stephen Powell)

World News Headlines – Yahoo! News

Read More..

Nexus 10: Can Google Compete With the iPad? [REVIEW]

The Nexus 10

The Nexus 10 has a gorgeous 10-inch display with a resolution of 2560×1600.

Click here to view this gallery.

[More from Mashable: 13 Popular E-Books That Cost Under $ 3]

After finding success with the Nexus 7, Google expands its tablet lineup with the Nexus 10. The 10-inch tablet features an incredibly high-resolution screen and packs a lot of power into a thin, lightweight package.

Moreover, at a starting price of $ 399, the Nexus 10 is competing head-to-head with Apple’s fourth-generation iPad and Amazon’s 8.9-inch Kindle Fire HD. So how does the Nexus 10 stack up to other Android tablets? Can it compete with the iPad? To find out, we spent five days with the tablet.

[More from Mashable: Top 5 Apps Your Kids Will Love This Week]

Build Quality

Samsung designed the Nexus 10, but the look and feel is pure Google. The device is extremely light — but unlike some Android tablets (I’m looking at you, Galaxy Note 10.1), it doesn’t feel cheap.

The device has a nicely curved shape — almost oval-like. The two stereo speakers are nestled into the side and blend in with the backing. Speaking of the back, it’s rubberized and feels great in the hand. I never had a fear of dropping the tablet, its grippy nature adding a sense of substantiality to the device in spite of its svelte frame and weight. The back of the device can get warm with heavy use, but it doesn’t feel hot.

The device weighs a bit less than the third-generation iPad and is just as thin (technically it’s even thinner but we’re talking half a millimeter, which is almost impossible to quantify by sight or touch).

The only odd part of the device is how the Nexus 10 Book Cover connects. There is a plastic panel at the top of the rear side of the device that can be removed. From there, you snap the cover into place. The cover works like a Smart Cover — lift it up, the device turns on. The cover fits well and adds virtually no bulk to the device, but I dislike the method of getting it on and off.

In addition to a micro-USB cable which can be used for charging, there is also a micro-HDMI port and a 3.5mm headphone jack. Apparently there is also a dock connector for easy charging, but we haven’t seen accessories that support it yet.

The Screen

As with most tablets, the story behind the Nexus 10 is all about the screen. The Nexus 10 sports a super-high resolution 2560×1600-pixel display. To put that in perspective, my 27-inch iMac’s resolution is 2560×1440.

This gives the the Nexus 10 a higher pixel density than even the iPad. In actual real-world usage, I genuinely couldn’t tell the difference between the clarity of the two displays. I tried with text and with the same 1920×1080 video file — both looked fantastic.

Blacks on the Nexus 10 are very black and colors pop. I used the screen in a variety of lighting conditions and only in direct sunlight did I have an issue with the screen. Bottom line: It’s great.

Of course, the one downside of having such a high-resolution screen is that just like with the iPad Retina, imperfections are readily apparent. For instance, while Google has updated all its app icons to look great on the high resolution screen, most other app makers haven’t.

Because of the way Android’s user interface elements are built, most apps tend to look fine on the high resolution display — even without specific optimizations — but apps that use bitmaps for UI elements/buttons or core graphical components and don’t have high-resolution assets will look pixelated.

The web is really the biggest culprit — most websites haven’t shifted to a Retina-ready web. That’s improving as more high-resolution displays enter the market, but a caveat of having such a high-resolution display is that some sites and images just won’t look great. I think it’s a worthy trade-off for everything else you get with a high-density display.

The Nexus 10 has a 16:10 aspect ratio. This makes the screen well-suited for video and certain games, but maybe not as ideal for reading books or magazines.

Bottom line: The screen is fantastic.

The OS

With Android 4.2, Google has an interesting way of refining its existing Android experience. To wit, 4.2 still has the name “Jelly Bean,” same as Android 4.1. Unfortunately, I was unable to test some of the newest 4.2 features with the Nexus 10 because they aren’t ready. When the devices start shipping to customers, Google says the update will be in place.

I’m a big fan of Android 4.1/4.2, especially on a tablet. Because this is a Nexus tablet, it avoids using any skins such as TouchWiz or Sense. This is a good thing, because I find that the pure Google experience is getting better and better.

With other large-screen Android tablets we’ve reviewed, I’ve often run into force-closes and problem managing memory. That’s not the case with the Nexus 10. I didn’t see any force-close errors, and the OS managed tons of running apps without a hitch.

I did find that the tablet was less buttery smooth than the Nexus 7. This was particularly true when scrolling in web pages or in some third-party apps. I wouldn’t call it sluggish — but there is a sense of lag that you don’t see on the Nexus 7 or on the iPad.

If you’re new to Android, the Nexus 10 is a good starter device because Jelly Bean 4.2 strikes a nice balance between working out of the box and offering options for more personalized customization.

Battery Life and Performance

The Nexus 10 boasts a huge 9000 mAh battery. I wasn’t able to run conclusive battery tests, but I’ve only had to plug it in once since Wednesday — and that’s with fairly continuous use.

The dual-core A15 processor is extremely fast and I didn’t sense any lag with high-resolution graphics or games. Playing Grand Theft Auto III was lag-free.

Google says the Wi-Fi on the device is better than the competition — but in my tests, I couldn’t see any benefits or deficits against my other gear. I have a dual-band 802.11n router and typically run everything off of 5Ghz N for minimal interference. NFC and Bluetooth are also built into the tablet and both worked well.

The Nexus 10 has two cameras — a rear 5-megapixel camera and 1.9-megapixel front camera. Both are unremarkable. The front-facing camera works well for Skype or Google+ hangouts. The rear camera is acceptable, if not outstanding.

The Nexus 10 is a solid performer and it compares well with the iPad and other large-screen tablets on the market.

Apps (Or Lack thereof)

The biggest problem with the Nexus 10 has nothing to do with the hardware itself. It’s the apps. Or more directly, the tiny number of apps optimized for its display.

While Apple is proud to boast about its 275,000 iPad-optimized apps, Google is nearly silent about the number of apps designed for for Android tablets. Worse, the discovery process for apps optimized for large-screen Android tablets is nearly non-existent.

This is less of a problem for smaller tablets, such as the Kindle Fire HD and the Nexus 7. After all, with 5-inch phones in the wild, scaling up for a 7-inch form-factor isn’t much of a stretch. When it comes to a 10-inch device, however, upscaled phone apps aren’t a great user experience.

More distressingly, the number of big-name apps with Android tablet-optimized versions is ridiculously small. Twitter doesn’t have an Android tablet app. Neither do Rdio, Spotify, The Weather Channel, The New York Times, eBay, LinkedIn, Skype (though Skype works just fine with tablets), Dropbox and many, many more. For the most part, the non-tablet versions of the apps work just fine on the Nexus 10, but the overall experience leaves something to be desired.

Flipboard is available on Android phones and on smaller tablets but I couldn’t even install it from Google Play. I was able to install the app via Amazon’s Appstore, but was presented with a warning that the app hadn’t been optimized for such a large screen. Sure enough, I wound up looking at an upscaled version of the phone interface, rather than a tablet.

In recent months, Google has started to take a more proactive approach, advising developers on tablet guidelines and curating collections of tablet-ready apps, but it doesn’t change the fact that finding apps to take advantage of the Nexus 10′s display is difficult in the best of circumstances.

Ultimately, I keep harping on the app situation because it’s the biggest issue facing not just the Nexus 10, but all large-screen Android tablets. Until the app situation is addressed in a meaningful way, it’s hard to recommend the Nexus 10 over the iPad — and that’s a real shame.

Using the Device

App issues notwithstanding, I found myself really enjoying the Nexus 10, especially for web browsing and watching video.

The tablet is light and its feather weight was really evident when I went back to my third-generation iPad after spending a few days with the Nexus 10 non-stop. The iPad felt heavy by comparison and I missed some of Android’s best features — such as easy access to settings from any screen.

I do want to note that as much as I enjoyed the tablet in landscape, I didn’t love using it in portrait. It’s just too tall and too narrow. I read a lot on my iPad — especially magazines — and the experience is nearly perfect. We’ll be discussing the magazine situation on the Nexus 10 (and Android in general) in a future article, but suffice to say, it’s not as enjoyable on a 16:10 device because the ratio really works against reading.

The same is true for reading regular books. Where the Nexus 7 makes a perfect sized e-reader, the Nexus 10 suffers because of its size. Books are best read in two-page side-by-side mode in the Kindle and Google Books apps, but in portrait, the screen feels too narrow.

Final Verdict

There are so many great things about the Nexus 10 — its screen and build quality, its great battery life and fast performance — not to mention the UI enhancements with Android 4.2. It’s a really solid device, except for one glaring, unavoidable reality: The apps.

Google has done an admirable job with all of its apps, and for those who never stray from the Google ecosystem, the tablet is a joy to use. For everyone else, using upscaled phone apps (often with forced orientations) is a frustrating use of what is otherwise such an excellent tablet.

For the average user, I’d have a hard time recommending the Nexus 10 over the fourth-generation iPad, because the iPad’s extra $ 100 cost is worth the greater tablet ecosystem. But the Nexus 10 is far and away the best large-screen Android tablet hardware I’ve used. If nothing else, it’s a solid example of what is possible on Android. With any luck, it will encourage Android developers to start making tablet-friendly apps.

What do you think of the Nexus 10? Sound off in the comments.

This story originally published on Mashable here.

Tech News Headlines – Yahoo! News

Read More..

Modest results in program to reduce kids’ screen time

NEW YORK (Reuters Health) – A program aimed at reducing the number of hours young children spent in front of a screen didn’t accomplish that goal, but it did cut back on the meals they ate in front of a television, a new study found.

That’s good news according to the lead author, because people tend to eat more and eat unhealthy food while watching television.

“The relationship between screen time and obesity is linked to eating in front of a screen,” said Dr. Catherine S. Birken, a pediatrician at The Hospital for Sick Children in Toronto.

In addition to its association with obesity, the study’s researchers say screen time – whether it is in front of a television, computer or video game console – has been linked to children having problems with language development and behavior, and their likelihood of cigarette smoking.

“These are really important health outcomes in young children,” said Birken. “So we need to understand what works and what doesn’t.”

So far, studies scrutinizing various methods of cutting back on kids’ screen time have found little success.

However, Birken told Reuters Health that a couple of past studies did find promising results in preschool children, which is why her team decided to test a practical approach in that age group.

For their study, published in the journal Pediatrics on Monday, Birken and her colleagues recruited three-year-old children from a network of clinics around the Toronto area during their annual checkups. The children and their parents were randomly assigned into one of two groups.

In an intervention group of 64 children, the parents were told about the health impact of screen time on kids and how to reduce their children’s hours.

Some of the techniques included removing televisions from the kids’ bedrooms and not allowing them to eat with the television on.

Those families, along with a control group of 68 similar children and their parents, were also educated about safe media use, such as rating systems, Internet safety and violent programming.

The researchers then looked to see if the children’s viewing or eating habits changed when they returned for a checkup a year later.

“TAKING IT SERIOUSLY”

Overall, the amount of time the children spent in front of a screen did not significantly differ between the two groups.

At the end of the study, the children in both groups spent between 60 and 65 minutes in front of a screen on weekdays. On the weekends, they spent between 80 and 90 minutes in front of a screen.

There also wasn’t a difference in the children’s BMI scores – a measure of weight in relation to height – between the start and end of the study. However, Birken said (for statistical reasons) she would only expect to see that in a larger group of children.

But, there was a statistically significant difference in the number of meals the children in the intervention group ate in front of the television.

At the start of the study, each group of kids ate about two meals with the television on daily. A year later, that number remained the same for the control group, but fell to about 1.6 for the intervention group.

That, the researchers note, works out to be at least two fewer meals per week in front of the television.

“I don’t think there is much harm in turning the TV off during meals. I think that is a good message either way,” said Birken.

But, she added that her team would have liked to see the kids spending less time in front of a television. She said it could be that the program needs to be spread out across society, including the children’s doctors and teachers.

Dayna M. Maniccia, an assistant professor at the University of Albany who has researched screen time interventions, said even if the study didn’t show a reduction in screen time, it makes people think about it.

“The new study is great because it means that people are looking at this and pediatricians are taking it seriously,” said Maniccia.

SOURCE: http://bit.ly/uFc4g2 Pediatrics, online November 5, 2012.

Parenting/Kids News Headlines – Yahoo! News

Read More..

HSBC earmarks more for US fines

5 November 2012 Last updated at 03:47 ET

HSBC bank has put aside a further $ 800m (£500m) to cover potential money-laundering fines in the US as it announced a fall in quarterly profits.

The bank had already put aside $ 700m after a US Senate report published in July said lax controls had left it vulnerable to money laundering.

Pre-tax profit for the three months to the end of September was $ 3.5bn, down $ 3.7bn from a year earlier.

However, the bank said underlying profits in the quarter had increased.

They totalled $ 5bn, more than double the figure recorded for the same quarter a year ago.

Europe’s largest bank also put aside a further £223m to cover UK payment protection insurance (PPI) mis-selling claims. This brings the total the bank has set aside for PPI compensation to £1.3bn and the total for the UK banking industry as a whole to almost £13bn.

BBC News – Business

Read More..

Barnes & Noble Drops Price of Nook Color and Tablet

In what is surely a response to the release of its Nook HD and HD+, Barnes & Noble announced Saturday it will lower the price of its Nook Color and Nook tablets beginning Sunday.

[More from Mashable: Barnes & Noble PIN Pads Hacked at Stores Nationwide]

The Nook tablet will now sell for $ 159 and the Nook Color for $ 139. The price represents a drop of $ 10 and $ 20 respectively.

[More from Mashable: Microsoft and B&N Name Joint Venture: Nook Media]

The company will release its 7-inch Nook HD and 9-inch HD+ on Nov. 8 in time for the holidays. They are priced $ 199 and $ 269 respectively.

Barnes & Noble Nook HD+

With the Nook HD+, Barnes & Noble both takes on the iPad and gives the recently unveiled Kindle Fire HD tablets a serious competitor. The big-size Nook tablet is priced at $ 269 for the 16GB model and $ 299 for 32GB. It’s also 2.8 ounces lighter than the Kindle Fire HD, but it doesn’t have any cameras.

Click here to view this gallery.

This story originally published on Mashable here.

Tech News Headlines – Yahoo! News

Read More..

“Breaking Bad” to get the “MythBusters” treatment

LOS ANGELES (TheWrap.com) – Finally, the world might find out if it’s truly a bad idea to dissolve a body with hydrofluoric acid in a bathtub.

Discovery Channel‘s reality show “MythBusters” – which re-enacts scenarios from movies, TV and urban legend to test their accuracy with scientific methodology – is filming a “Breaking Bad”-themed episode, a spokesman for the cable network told TheWrap on Friday.

“Breaking Bad” creator Vince Gilligan and star Aaron Paul – who plays meth manufacturer Jesse Pinkman on the series — will be on hand as “MythBusters” stars Jamie Hyneman and Adam Savage put the logic of the hit AMC drama.

No other details, such as when the episode will air, were available.

Back in June, Gilligan said in an interview that he’d like to do a “Breaking Bad”/”MythBusters” crossover.

“I’d dig seeing those guys prove or disprove some of the crazy stuff we’ve done on ‘Breaking Bad,’” Gilligan enthused.

While they’re at it, perhaps they can get to the bottom of whether that electromagnet episode would have been possible in the real world.

EW.com first reported the news of the “Breaking Bad”/”MythBusters” crossover.

TV News Headlines – Yahoo! News

Read More..

Israel’s Neuronix offers new Alzheimer’s treatment

TEL AVIV (Reuters) – Israel-based Neuronix, which has developed a non-invasive medical device to help to treat Alzheimer’s disease, expects the system to be approved by the U.S. Food & Drug Administration in late 2014.

The device, which combines electromagnetic stimulation with computer-based cognitive training, is already approved for use in Europe, Israel and several Asian countries. In Singapore it is approved for clinical trial use and the application for registration of the product is still under evaluation.

“You stimulate the brain on a biological level as well as on a cognitive level,” Neuronix CEO Eyal Baror told Reuters, saying this double approach created longer-lasting benefits.

The device, which consists of a chair containing an electronic system and software in the back and a coil placed at the head, has been tested on mild to moderate Alzheimer’s patients who suffer from dementia but are not totally dependent.

The system is in trials at Harvard Medical School/Beth Israel Deaconess Medical Centre. Patients are treated for one hour a day, five days a week over six weeks.

“We see improvement lasting for 9-12 months and the good thing is that patients can return and undergo treatment again,” Baror said. “If out of 10 years the patients have left to live we can keep them at home in a relatively mild state of the disease for three, four, five years, it’s a lot.”

According to Alvaro Pascual-Leone, director of the hospital’s Berenson-Allen Centre for Non-invasive Brain Stimulation, brain stimulation – or transcranial magnetic stimulation – involves a very low current applied to a specific part of the brain and is approved by the FDA for treatment of a variety of ailments and diagnostic applications.

“The application in Alzheimer’s disease and in combination with cognitive training is novel,” Pascual-Leono said in a phone interview from Boston.

About 20 percent of patients experience a mild headache but there are no long-term negative effects, he said.

Pascual-Leone, who is principal investigator in the Harvard trial, said that of 12 patients in the study, six received the real treatment and all showed cognitive improvement. Their improvement was significantly more than the average seen in patients taking just medication, he said.

The study’s results will be submitted for publication in the coming weeks and a follow-up study on 30 patients is planned.

Neuronix received European approval several months ago and has installations in the UK and Germany. In Israel, a few dozen patients are being treated with the device.

The U.S. trials are expected to run till the end of 2013. Neuronix is also running a trial in Israel for pre-Alzheimer’s patients.

The company expects to sell half a dozen systems in the second half of 2012 and three dozen in 2013. In Israel, the treatment costs $ 6,000.

“Our target for becoming profitable is in parallel to entering the U.S. market around 2015,” Baror said.

Neuronix has raised $ 8 million from private individuals as well as in grants from the Israeli Chief Scientist’s Office and is exploring options to raise more money in the coming year, including the possibility of going public.

(This version of the October 24 story corrects paragraph two that company corrects to say that in Singapore, device is approved for clinical trial use and its application for registration of the product is under evaluation, not that device is approved for commercial use.)

(Reporting by Tova Cohen; editing by Stephen Nisbet)

Diseases/Conditions News Headlines – Yahoo! News

Read More..

Anglogold strikers return to work

2 November 2012 Last updated at 10:31 ET

Striking miners at two South African Anglogold Ashanti pits have agreed to return to work as tensions across the country’s mineral sector ease.

Hundreds of miners have been holding underground sit-ins this week at the Anglogold Ashanti site at TauTona and Mponeng 40 miles west of Johannesburg.

The strikers demanded early payment of a bonus, an Anglogold spokesman said.

South Africa’s mining industry has been wracked since the summer by widespread strikes and sporadic violence.

“In both these cases these people, who represent less than 2% and 5% of the respective workforces, returned safely to surface after holding talks with the mines’ management,” said Anglogold Ashanti in a statement.

Employees had been promised a 1,500-rand ($ 173, £108) bonus, a company spokesman said, but this would only be paid out “at a later stage, based on safety and attendance outcomes”.

Work at the mines, which employ 10,000 people, is expected to resume with the night shift on Sunday.

A series of strikes across the mining industry has crippled output and had a major effect on the economy since August.

Mass dismissals

Many other mining companies besides Anglogold have been affected by the industrial unrest, in which over 80,000 workers have downed tools.

Striking workers have been involved in several fatal clashes.

In the worst incident, more than 40 people died in August in clashes between police and striking workers at Lonmin’s Marikana platinum mine near Rustenburg, 120km (70 miles) north-west of Johannesburg.

Miners have primarily been demanding higher wages, while the owners have variously responded with offers of conditional bonus payments, or mass dismissals.

Anglo American Platinum has sacked and subsequently reinstated 12,000 workers at its site in Rustenburg, but the miners have so far refused to return to work.

One mine belonging to Gold Fields remains shut after 8,500 workers were fired for striking, while on Thursday Xstrata sacked 400 workers for an illegal strike at its Kroondal chrome mine.

South Africa is one of the world’s biggest producers of precious metals and has a huge coal-mining industry.

Also on Friday, striking coal miners at the Mooiplaats mine returned to work.

The colliery’s owner, Coal of Africa, has agreed to increase their wages by 26% retroactively from July this year, including medical care and allowances for housing, shift and underground work.

BBC News – Business

Read More..